Essay on ebola informative speech - 793 Words

Manuscript INTRODUCTION: ATTENTION GRABBER: Imagine being isolated from your own family and feeling unsure as to whether or not you will ever see them again. They do not want to come anywhere near you, for you are a threat to their health. The only visitors who come with in 10 feet of you are strangers in full on protective gear. They do not want to expose the slightest bit of skin to you and you can not see anything besides their eyes. The world fears what you are and no one wants to come close to you. You know death is near, and you are all alone. TOPIC: Today I will tell you about the rare and deadly virus called Ebola. PREVIEW: First, I will give you information about the virus itself. Secondly, I will talk about why†¦show more content†¦SECOND POINT: Although an outbreak in America is highly unlikely, the fact that Ebola has been diagnosed on American soil brings fear to all. Because of its infectiousness and long incubation period, and the banality of early symptoms, it can be difficult to track and contain. We also do not have a cure for this disease, sure we have experimental drugs, but nothing official. The spread has been much quicker in this outbreak than others, affecting both urban and rural areas. Usual protective measures to prevent the spread appear to be less effective in this epidemic. What ebola does to the human body defies reason and is something like out of a horror movie, not a text book. Americans feel hopeless and vulnerable because Ebola is here. The victim who flew from Liberia to Dallas, Texas on September 30th of this year did expose others and there is a risk of i t spreading. The Ebola virus is the most terrifying and least-understood virus known to man. We are witnessing the onset of a deadly mutation anticipated and feared for almost four decades. Americans have watched fully informed and trained health care workers contract Ebola. **3rd Transition** Now that we are aware of the amount of fear, and why there is so much of it, lets turn our attention to some methods of prevention. THIRD POINT: There is no FDA approved vaccine currently available for Ebola. It is very important that everyone practices careful hygiene. Always wash hands with soap andShow MoreRelatedEbola speech Essay1008 Words   |  5 Pagesï » ¿Ebola speech http://www.studymode.com/essays/Ebola-Informative-Speech-61391491.html http://www.who.int/mediacentre/factsheets/fs103/en/ Plan: introduction What is Ebola (some facts) How was is created Effects of Ebola aka symptoms Transmission Treatment How can Ebola affect us Imagine being isolated from your own family and feeling unsure as to whether or not you will ever see them again. They do not want to come anywhere near you, for you are a threat to their health. The only visitors who

Edmund Spenser vs. Virgil and Ariosto Essay - 1986 Words

Edmund Spenser vs Virgil and Ariosto Some scholars believe Spenser did not have sufficient education to compose a work with as much complexity as The Faerie Queene, while others are still â€Å"extolling him as one of the most learned men of his time†. Scholar Douglas Bush agrees, â€Å"scholars now speak less certainly that they once did of his familiarity with ancient literature†. In contrast, Meritt Hughes â€Å"finds no evidence that Spenser derived any element of his poetry from any Greek Romance†. Several questions still remain unanswered: Was Edmund Spenser as â€Å"divinely inspired† to write The Faerie Queene as Virgil and Ariosto were in their works? Or did Spenser simply lack creativity, causing him to steal his storylines from†¦show more content†¦Another scholar testified that both Ariosto and Spenser did not observe Virgil’s conception of an epic as ‘a unified account of a single hero’s career,’ but inste ad got lost in their concentrations on wild, unnatural allegories that greatly displeased and ultimately confused the reader (1). Spenser, who was referred to as the â€Å"English Virgil† by his contemporaries, was certainly influenced by Virgil’s success (Kennedy 717). The idea of modeling one’s career after Virgil’s is know as the rota Virgilli or cursus Virgilli, meaning â€Å"the Virgilian wheel or course† (717). It is explained in a four-line preface added to Renaissance editions of the Aeneid: ‘Ille ego, qui quondam gracili modulates avena/ Carmen, et egressus silvis vicina coegi/ ut quamvis avido parerent arva colono,/ gratum opus agricolis, at nunc horrentia Martis’ (I am he who, after singing on the shepherd’s slender pipe and leaving the wood-side for the farmlands ever so much to obey their eager tenant; my work was welcome to the farmers, but now I turn to the sterner stuff on Mars)(717). Virgil starts off writing the pastoral poem and ends with the epic. He begins his career with â€Å"shepherd’s slender pipe (the pastoral Eclogues), proceeds to the ‘farmlands’ (the didactic Georgics), and finally arrives at the ‘sterner stuff on Mars’ (the epic Aeneid)† (717). Spenser described his own career similarly in the first book of The Faerie Queene: ‘Lo I the man, whose Muse whilome

Engine Free Essays

Assignment 1. 1 Communication Process Model 1. 1 Communication Process Model A misunderstanding I experienced communicating with a co-worker at work. We will write a custom essay sample on Engine or any similar topic only for you Order Now Misunderstanding 1 Who was the sender? Myself Who was the receiver? Another co-worker What was the message? Was to lack and inspect the Air plane lack system that holds the cargo pallets. What channel was used to send the message? Verbal face to face communication What was the misunderstanding that occurred? Coworker didn’t understood my instructions because of the commotion, loudness and the amount of cargo that need to be loaded as we were doing everything fast and there was not enough time. How could the misunderstanding have been avoided? We should have had a time to stop and listen to each other to convey the message. Cite meaningful understanding rather than a general or less material misunderstanding. Use business- or work-related examples. Identify the roles of the sender and receiver, such as manager, peer, subordinate, client, vendor, and so forth. 1. What did you learn about the communication process from this activity? What I learned from this activity was that the when communicating to someone the process is not as easy as it looks when relaying the message to a received correctly. My position was to stop and ask the coworker to just regroup to have meeting which allowed me to tell him to correct any problems or issue that he can make when inspecting the lacks as this is critical to an aircraft can cause a major problems. It also give me understanding that when you give directions as to what and how something works you need to send a message clearly to a receiver. The coworker because of the time and commotion he did not inspected and didn’t receive my message clearly. The communication needed more time an understanding. 2. What seemed to be the main causes of the misunderstandings? The main cause of the misunderstanding was all the commotion in the ramp where all aircrafts are park as we have many people assigned to a plane. Neither one of us took the time to stop and listen to each other which created difficulties to the loading of the aircraft. At the end we came to a conclusion that we needed to communicate more within the employees and management to have a meeting or PCM every morning before everything start to have a communication process and eliminated a great deal of problems and misunderstandings. Misunderstanding 2 Who was the sender? Manager Who was the receiver? Myself What was the message? Promotion with same schedule. What channel was used to send the message? Verbal communication What was the misunderstanding that occurred? That I was being promoted to lead loader but would still need to have to work on the weekends as many departures took place, but as I had spoke to him before I need it the weekends off for my Family. How could the misunderstanding have been avoided? My Manager did not quite understand my point. He also needed to explain his communication more clearly. 1. What did you learn about the communication process from this activity? This activity taught me that people need to communicate properly and clearly. I was promoted to lead loader from just coordination of loading since I was the last person to be promoted then, discovered that I was expected to keep working on the weekends so other team could schedule off. 2. What seemed to be the main causes of the misunderstandings? The main cause of the misunderstanding was management communication was not clear to me since before I had asked for the weekends off to be with my family even dough I was being promoted. It took me more talks with HR and upper management to resolve this issue. The problem could have been avoided if manager could have been more clearer and explain why he wanted me to work on the weekends this could have avoided me to talk to other upper managers How to cite Engine, Papers

On Michel Foucault’s Surveillance Society Essay Sample free essay sample

The constructs â€Å"modem† and â€Å"post-modern† have become common currency in rational arguments. Within such arguments. the postmodern is perceived as an era. a position. or an wholly new paradigm of idea. Such a construct of the aforesaid term stems from its rootedness in the construct of the modern. Chia notes that what distinguishes the postmodern from the modem is â€Å"a manner of believing which eschews the noncritical usage of common footings such as ‘organizations’ . ‘individuals’ . ‘environment’ . ‘structure’ . and ’culture’ . etc† ( 1995. p. 579 ) . These footings refer to the being of societal entities and properties within a modernist construct of societal world. The principle behind this lies in the ontological construct of being which privileges believing in footings of distinct phenomenal provinces. inactive properties and consecutive events. As opposed to such an ontological construct of world. the postmodern stands as the title-holder of weak signifiers of ontology that â€Å"emphasize a transient. passing and emergent reality† ( Chia. We will write a custom essay sample on On Michel Foucault’s Surveillance Society Essay Sample or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page 1995. p. 579 ) . If such is the instance. it thereby follows that a postmodernist position of world adheres to believe manners wherein world is deemed to be continuously in flux and transmutation and hence unrepresentable thereby impossible to locate within a inactive construct of world. An acceptance of a post-modernist position of world thereby leads to a rethinking of the modern constructs of societal world since attachment to postmodernist positions lead to the de-emphasis on signifiers and properties. Such a construct of world ; nevertheless tends to stress the importance of local methods. which jointly define a societal world. In a sense. the displacement from a modern to a postmodern construct of world thereby leads to the re-definition of bing ontological constructs of world that determine the assorted signifiers of rational precedences every bit good as theoretical judicial admissions in the survey and construct of being. Such a perceptual experience of world [ that is extr emely characterized by the postmodern bend ] is apparent in Michel Foucault’ perspectives as to the workings of societal world. Michel Foucault’s usage of Jeremy Bentham’s construct â€Å"panopticon’ in his bookDiscipline and Punishnowadayss a treatment of the facet of surveillance while puting accent on a cardinal alteration and interrupt ensuing from the alterations in the societal and theatrical agreements during the 1800’s. The difference in methodological analysis is apparent if one considers that every bit opposed to the old methodological analysis wherein the many see the few. modern methodological analysis has enabled the displacement wherein the few see the many. Foucault notes that such a displacement shows the mode in which â€Å"the instantaneous position of a great multitude† is procured for a little figure or even for a individual person ( 1974. p. 216 ) . He farther notes that the deductions of such show the mode in which Our society is one non of spectacle. but of surveillance†¦We are much less Grecian than we believe. We are neither in the amphitheatre. nor on the phase. but in the panoptical machine. invested by its effects of power which we bring to ourselves since we are a portion of its mechanism. ( Foucault. 1974. p. 217 ) Such a position is based on the premise that society stands as the venue for the interplay of assorted signifiers of power dealingss. Such signifiers of power relation determine the mode in which an person situates himself/herself within his/her milieus. Surveillance. in this sense. may be seen as a method which society inscribes upon an person as he/she chooses to modulate his/her actions dependent upon the signifier of power relation in which he/she has direct entree. It is of import to observe. that Foucault’s impression of panopticonism besides emphasizes the being of freedom within a predefined infinite. Understanding power is cardinal to understanding Foucault’s analysis of subjectiveness. Foucault explicitly rejects the paradigm of power as repression. reasoning that power is non merely negative but besides productive. He rejects the juridical theoretical account of power. wherein power is characterized as inhibitory. rule-based. uniform. and prohibitory. Harmonizing to this theoretical account. the topic is constituted as one who obeys this negative one-sided power. Foucault characterizes power as positive and productive. Power is everyplace. a multiplicity of force dealingss ; it is ever local and unstable. This ubiquitousness of power does non prevent opposition. On the contrary. opposition ( s ) can merely be in the strategic field of power dealingss. Power is action that runs through and between things ; power is first and first relational. Not merely is power ever a relationship. but power relationships exist everyplace. Freedom. in this sense. is to be understood as composed of positive and negative facets. Although one exists within panoptical society. it is possible to prosecute in instances of positive freedom through the battle of actions. which contradicts the dominant discourses. In the popular womens rightist motions. for illustration. such an act involves the redefinition of the feminine as opposed to the presumed patriarchal construct of the female. Such is the mode in which Foucault’s doctrine emphasizes the fluidness of constructions despite its being within a panoptical kingdom. Mentions Chia. R. ( 1995 ) â€Å"From Modern to Postmodern Organizational Analysis† .Organizational Surveies16: 579-604. Foucault. M. ( 1974 ) .Discipline and Punish The Birth of the Prison.New York: Vintage.

Manipulation in Documentaries free essay sample

Every night when we sit down to watch our much loved Grey’s Anatomy or Desperate Housewives, we know for a fact they are fictional dramas which allow us to escape the reality and boredom of our lives. We also realise the scripted shows use many tactics to manipulate our thinking. The producer does this to position us towards a specific view of life. But what do we expect from a documentary? We know documentaries to be faithful recounts of events; however, these events may be subject to just as much manipulation as the intriguing plots in our addictive shows. Many documentary makers include their individual cultural assumptions and discourses to distort the truth and position the target audience to react in a desired manner. This can be seen in the documentary, ‘Supersize Me’ by Morgan Spurlock and ‘Great White – Deep Trouble’ showcasing Peter Benchley, David Doubilet and Rodney Fox. Both producers desire to position the audience towards their discourse through their documentary. We will write a custom essay sample on Manipulation in Documentaries or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page They accomplish this by presenting snippets of films, opinions and facts that agree with their discourse and disposing of the rest. ‘Super Size Me’, written, produced, directed by and starring Morgan Spurlock, is a producer dominated documentary. It shows Spurlock endeavouring on a thirty day McDonald’s binge to prove that regular consumption of the food is a fast way to heart disease, high cholesterol and obesity. Spurlock aims to prove his nutritional discourse by taking tests before and after the experiment to show the affects. Before the experiment began, Spurlock’s body showed healthy results both physically and emotionally, however, after the experiment, his body was physically rundown sporting clogged arteries, high cholesterol, weight gain and emotionally he showed early stages of depression. Spurlock’s aim in the documentary is to inform his audience that regular fast food consumption is extremely harmful to your body. It uses both fully narrated and self reflexive types of documentary to present the message. This means voice overs are used to interpret graphs, pictures and facts presented in the documentary to prove that fast food has a significant impact on the nation’s health. He also includes many techniques including camera angles, music and sound, lighting and many elements typical of documentaries. Spurlock uses Mise-en-scene to prove that obesity is a result of extreme fast food intake by purposely filming obese people walking through a shot at McDonalds. Spurlock also uses the technique of interviewing doctors and scientists to grab our attention and make it difficult for us, the audience, to make our own decision. He does this as the majority of us believe scientists and doctors have the most knowledge on this argument and therefore we will agree with his discourse. Similarly the documentary, ‘Great White – Deep Trouble’, produced by John Bredar, attempts to influence the audience to feel sympathy and love for the Great White which to many represents a killer beast. The documentary aims to manipulate us towards the view that sharks are gentle fish that are simply misunderstood by humans. Through the journey of David Doubilet, a famous photographer, the audience are presented with pictures, journal entries and filming of the Great White in the hope of capturing the perfect shot. One of the crew on the mission is Rodney Fox who previously had a bloody encounter with a Great White and survived. Although the majority of us would be too afraid to return to the water, Fox has chosen to partake in the mission of defending the creature. The producer uses this to his advantage by demonstrating that even someone who was attacked by a killing machine managed to love the animal and therefore we should too. The documentary uses techniques in order to create a calm ambience and make the shark seem vulnerable. They use relaxing music and bright lighting to create a sympathetic and almost angelic view of the shark. Camera shots are taken under water allowing the audience to see the scenery and true characteristics of the shark. The documentary provides close up shots to shows the sharks facial features and emotions. It also uses long shots to show the entire body and the provide insight into the sharks natural habitat. The documentary uses the feature of exposition to expose the true qualities of the shark in order to manipulate the audience. Both documentaries possess intertextualities that we are all familiar with. In general, when we see Ronald McDonald we are automatically reminded of McDonalds and their food products. In the Documentary, Spurlock shows Ronald McDonald as an evil clown rather than happy. This represents his negativity towards the restaurant. When watching ‘Great White – Deep Trouble’ our intertextualities towards sharks is that they are vicious man-eating machines like the shark off the movie ‘Jaws’. Although many facts, graphs and discourses are exposed and explained throughout these two documentaries it does not necessarily mean the producer’s opinion is correct. They simply want to manipulate and position the audience to believe what they say in order to sell their view to the public. When we hear the word,’ documentary’ our cultural beliefs tell us they are filled with true facts or recounts of events, however, we need to realise that documentaries are filled with individual discourses which aren’t essentially accurate. We as an audience need to ensure we do not fall victim to the producer’s manipulative techniques that are incorporated in the documentaries. In order to do so we need to be strong in our personal beliefs and discourses. That does not mean you should seclude all opinions from others. Be open to new ideas, but be strong in your own beliefs. That way you will not be manipulated as easily. Make your own decision and don’t let the producer sway that conclusion.

Ethical Considerations in Respect of Advertising, Sales Promotion, Pricing, Product Packaging and Obsolescence Essay Example

Ethical Considerations in Respect of Advertising, Sales Promotion, Pricing, Product Packaging and Obsolescence Essay Example Ethical Considerations in Respect of Advertising, Sales Promotion, Pricing, Product Packaging and Obsolescence Paper Ethical Considerations in Respect of Advertising, Sales Promotion, Pricing, Product Packaging and Obsolescence Paper Assignment: Ethical considerations in respect of advertising, sales promotion, pricing, product packaging and obsolescence. 2011 Introduction Ethics is concerned with what is right and what is wrong. Ethics relate to moral evaluations of decisions and actions as right or wrong on the basis of commonly accepted principles of behaviour (Dibb et. al. , 1997), in other words, ethics are the moral principles and values that govern the actions or/and decisions of an individual or group. They serve as guidelines on how to act rightly and justly when faced with moral dilemmas. Sometimes the line between what is considered ethical and unethical is difficult to distinguish since what is right and wrong differs depending on such factors as nationality, culture, sex etc. Ethics is individually defined and may vary from one person to another. Many people wrongly assume that only actions that violate laws are considered unethical. Some activities can be unethical even though no laws are violated, for example, it can be considered as unethical activity for companies to aggressively promote unhealthy food to children though such promotional practices are generally in the world not viewed as illegal. It is believed that good marketing is ethical marketing. Practicing ethics in marketing means deliberately applying standards of fairness, or moral rights and wrongs, to marketing decision making, behaviour, and practice in the organization. While the most basic ethical principles have been codified as laws and regulations to conform to the standards of society, marketing ethics goes beyond legal and regulatory issues. Ethical marketing practices and principles are the main that establish trust, which will help to gain and maintain the reputation of the company and to build long-term marketing relationships. The purpose of this assignment is to define and explain ethical marketing considerations in respect of advertising, sales promotions, product quality, packaging, obsolescence, pricing and consumer manipulation. Promotion and advertising Some marketing activities may create ethical issues, for example, false, misleading and negative advertising, manipulative or deceptive sales promotions etc. An ethical issue is an identifiable problem, situation or opportunity requiring an individual or organisation to choose from among several actions that must be evaluated as right or wrong, ethical or unethical. Any time any marketing activity causes customers to feel deceived, manipulated or cheated, a marketing ethical issue exists, regardless on the legality of that activity (Dibb et. al. , 1997). The visibility of advertising, coupled with its role as persuasive communication, results in it being the area of marketing most affected by ethical issues. The major ethical issues in advertising and sales promotion are their misleading or deceptive aspects and the social harm attributed to advertising. Unethical actions in advertising can destroy the trust that customers have in the company. First to mention is false, deceptive or misleading advertising. As advertising has the potential to persuade people into commercial transactions that they might otherwise avoid, many governments around the world use legal regulations to control false, deceptive or misleading advertising. An advertisement is deceptive if there is a representation, omission or practice that is likely to mislead consumers in a material way – and is therefore ethically wrong. Advertisers must be able to substantiate claims about product performance. Second to mention is advertising that involves ambiguous statement – statements using words so weak that the viewer, reader or listener must infer advertisers’ intended messages (Dibb et. al. , 1997). Third to mention is advertising that involves violence, profanity and propaganda of sex. Fourth to mention is attack advertisements that unfairly denigrate competitors, so called negative advertising. In negative advertising, the advertiser highlights the disadvantages of competitor products rather than the advantages of their own. Sales promotion Personal selling as a type of sales promotions is to be mentioned regarding ethical issues, because some consumers may perceive salespeople as an unethical when persuading and pressing to purchase the products that they neither need nor want, so called high-pressure selling. A common problem in personal selling is judging about what types of sales activities are acceptable and what are not. Although most sales people are ethical, some do engage in questionable actions, such as aggressive and manipulative tactics, or not telling the customers the truth about the product, or making customers to believe that they will get more value than they actually do. Deceptive or misleading promotion â€Å"includes practices such as overstating the products’ features or performance, luring the customers to the store for a bargain that is out of stock, or running rigged contests† (Kotler et. l. , 2002). Pricing Ethical pricing means such type of pricing so as to avoid taking undue advantage of the highly price-inelastic demand for a product (Schoell, 1990). Price fixing (bid rigging), predatory pricing (dumping), failure to disclose the full price associated with a purchase, price discrimination, price skimming, price cartels and price wars are typical ethical issues in pricing policies. Most of the pricing policies mentioned above are illegal. The emotional and subjective nature of price creates many situations in which misunderstandings between the seller and buyer cause ethical problems. Marketers have the right to price their products so that they earn a reasonable profit, but ethical issues may crop up when company seeks to ear high profits at the expense of its customers. (Dibb et. al. , 1997). Product packaging Deceptive packaging includes exaggerating package contents through subtle design, not filling the package to the top, using misleading labelling, or describing size in the misleading terms (Kotler et. l. , 2002). Product obsolescence Product obsolescence can be planned and functional, planned obsolescence means a strategy of causing products to become obsolete before they actually need replacement (for example, electronics, fashion and computer industry) (Kotler et. al. , 2002), but functional obsolescence occurs when technological breakthroughs render an existing product out-of-date. Three types of planned obsolescence exist: postponed, internationally designed and fashion or style. Postponed obsolescence means holding back and adding product improvements until present inventories run out or demand falls out sharply. Internationally designed obsolescence involves designing a product, or a critical part, to wear out within a given period of time. Fashion or style obsolescence is psychological – new model cars make last year’s models obsolete (Schoell, 1990). References: Dibb, S. , Simkin, L. , Pride, W. M. , Ferrell, O. C. (1997), Marketing, Concepts and strategies, Third European edition, Houghton Mifflin Company, U. S. A, pp. 738-49. Kotler, P. , Armstrong, G. , Saunders, J. , Wong, V. (2002), Principles of marketing, Third European edition, Pearson Education Limited, Edinburgh, England, pp. 43-68. Schoell, W. F. , Guiltinan, J. P. (1990), Marketing contemporary concepts and practices, Fourth edition, Allyn anb Bacon, Massachusetts, pp. 27-29, 60-64, 313, 649.

How would you suggest this should be done Are any of these subsystems Assignment

How would you suggest this should be done Are any of these subsystems more or less important than any others - Assignment Example For example, it will be impossible to attain the mission of an organization without having a clear vision and/ or objective. Examples of subsystems within organizations include goals and values subsystem, human resources subsystems, information and intelligence subsystem, technical subsystem, managerial subsystem and structural subsystem. According to Baskerville and Spagnoletti (2013), the continual interaction between various subsystems creates a pattern that specify what the main system looks like and therefore, it is impossible to gauge the main organizational system by over passing a particular subsystem since the main system relies on interdependent sub-systems. Therefore, when trying to evaluate the strengths and weaknesses of an organization it is a must for all the subsystems to be considered since an organizational is a functional unit that can only operate smoothly with the co-operation and co-ordination of various subsystems which are interdependent to each other. This is to mean that no sub-system is more or less important than the other since an organization cannot operate without a single subsystem missing and hence the evaluation should consider the strengths and weakness of each subsystem in the

Staffing Plan Paper Essay Example | Topics and Well Written Essays - 1000 words

Staffing Plan Paper - Essay Example Developing a strategic plan for staffing in a transport or distribution company is one thing that helps many it in making the right choice of what best they want for themselves (Bechet, 2008). In this step, a human resource manager or the person in charge of this activity has to collect information basing on the kind of service provided by the current employees. This information gathered is very important for companies because they help when enforcing some training and also in the case when the company promotes its employees. After getting the information needed about the available staff members, one can use it in finding out the average input provided by each employee in accordance to the number of hours (Bechet, 2008). An example can be drawn from a transportation company which depends on the number of trips made by drivers in determining ones capability. Most of the companies around the world do have some of the seasons that they consider much busy while other seasons are not taken as such. During the busiest seasons, one can use the statistics in determining the kind of need the company requires for the purpose of making the best from what they have. For instance the transportation company has to have more vehicles during the busiest seasons because this is a time when a company’s products are very much competed in the market. With more vehicles for the purpose of transportation means that the available products will get to the market on time, improving the company’s supply. The fourth step in the staffing plan is determining the number of employees the company requires in terms of drivers responsible for the transportation activity. This must comply with both the busiest seasons and the less busy ones. An additional number of vehicles mean that more drivers have to be employed by the company while having less vehicle leads to the current employees or drivers being overworked

Is Nuclear power our gate to the future (with nuclear or against ) Essay

Is Nuclear power our gate to the future (with nuclear or against ) - Essay Example The information comes from reputable sources such as the U.S. Nuclear Regulatory Commission, U.S. Department of Energy, Energy Information Administration, and U.S. Atomic Energy Commission, Office of Planning and Analysis. The source has no bias because it presents a logical argument about a beneficial energy source that is expensive. I have chosen this source because it compares the cost of nuclear energy and other alternative energy sources. The author mentions ways for reducing the cost of construction of nuclear plants to make it affordable in the society. The main topic of the article is improving efficiency in nuclear power plants. It discusses innovative techniques and safety measures that can ensure nuclear energy plants maintain efficiency. The author supports nuclear power. He chooses this position because he believes that there are innovative measures that can ensure safety in nuclear power plants. Their arguments are based on latest research on technology that is useful in nuclear power plants. The source is credible because it discusses incremental innovations in the digital world, and enhancements of safety margins in an existing power plant. I have chosen this source because it provides a solution for risks involved in nuclear power plants. The dangers and effects of nuclear plants remain the greatest challenge that opponents of nuclear energy discuss. The main topic of the article is making nuclear energy sustainable. The paper analyzes and reviews the challenges that nuclear power must get through before the society accepts it as a sustainable energy source. Pearce is obviously against nuclear power as an energy source because it is not sustainable. He chose this position because of its associated environmental burdens, specifically greenhouse gas emissions and nuclear and radioactive waste disposal. In addition, he cites nuclear insecurity as a danger of nuclear energy,

RP-HPLC-UV Method for Simultaneous Estimation of Ceftriaxone

RP-HPLC-UV Method for Simultaneous Estimation of Ceftriaxone A Validated RP-HPLC-UV method for Simultaneous estimation of Ceftriaxone and Sulbactum in Rat Plasma ABSTRACT: A reverse phase-liquid chromatographic method with UV detection is developed for simultaneous estimation of ceftriaxone sodium and sulbactam sodium in rat plasma. Drugs were extracted from blank plasma by simple protein precipitation technique. Chromatographic separation of these two drugs was done on Phenomenex C18 column (250mm X 4.6mm, i.d, 5ÃŽ ¼m) by using mobile phase consisting of 10mM potassium dihydrogen orthophosphate buffer (pH- 5) and acetonitrile (90:10 % v/v). The developed RP-HPLC method had the acceptable symmetrical peaks good resolution and drugs were eluted with good retention time. The developed bio-analytical method was Linear, precise, and accurate with the concentration range of 20-150 ÃŽ ¼g mL-1 for ceftriaxone and 10-75 ÃŽ ¼g mL-1 for sulbactam. From the developed method we can moniter ceftriaxone and sulbactam sodium concentrations in rat plasma. Keywords: Ceftriaxone sodium, Sulbactam sodium, Liquid chromatography, Rat plasma INTRODUCTION Ceftriaxone[1] (CFX) is a third generation cephalosporin. Chemically it is (6R,7R)-7-{2-(2-amino-4-thiazolyl)-(Z)-2- [methoxyiminuteo-acetamido]-3{[(2,5-dihydro-6-hydroxy-2-methyl-5-oxo-as-triazin-3-yl)thio]methyl}-8-oxo-5-thia-l-azobicyclo [4,2,0] oct-2-ene-2-carboxylic acid. Sulbactam (SBM) chemically (2S,5R)-3,3-Dimethyl-7-oxo-4-thia-1- azabicyclo[3.2.0] heptane -2-carboxylic acid 4,4-dioxide is used as a beta-lactamase inhibitor. Structural formulae of CFX and SBM are given in Fig.1. These drugs are frequently associated in pharmaceutical formulations against meningitis, typhoid, gonorrhoea and urinary tract infections [2]. Sulbactomax is a commercially available pharmaceutical product containing SBM and CFX. The product is available as a dry powder for injection. The product is supplied in different strengths (250 mg+125 mg, 500mg+250 mg, 1gm+0.5gm, 2gm+1gm) of CFX and SBM respectively. Fig.1.Chemical structure of CFX and SBM Sulbactomax is a synergistic antimicrobial mixture with clear in vitro antibacterial activity against a wide spectrum of organisms. SBM not only increases the antibacterial activity of CFX but also shows a moderate antibacterial activity by forming a protein complex with beta-lactamas by irreversibly blockin their destructive hydrolytic activity. Thus, SBM increases the spectrum of activity of CFX. This SBM also binds with some penicillin binding proteins, sensitive strains are often considered more susceptible to the Sulbactomax than CFX alone. In bacterial strains that produce either low amounts of beta lactamase, or none at all, a synergistic effect is witnessed when SBM is associated with CFX that has a complementary affinity for the target sites. Sulbactomax has good active against all the microorganisms which are sensitive/resistant to CFX. Further, it also demonstrates synergistic activity (decrease in minimum inhibitory concentrations for the combination versus those of each component) in a variety of organisms. So it has improved efficacy as compared to CFX alone, lesser side effects, wider spectrum coverage and better results of bacterial MIC (minimum inhibitory concentration) makes this product unique in the world. A literature survey revealed a spectrophotometric [3], spectrofluorimetric in human plasma [4], HPLC for the estimation of marketed formulations [5,6], in human plasma [7] and for the determination of pharmacokinetics in dogs [8], capillary electrophoresis [9] and GC-MS [10] methods for the estimation of CFX and SBM individually and in combined forms. However, from the literature survey there was no method development reported for the simultaneous estimation of CFX and SBM by HPLC in rat plasma. The present communication describes an isocratic liquid chromatography (LC) method for simultaneous determination of CFX sodium and SBM, which can be used for the quality control of the formulation developed and other biological applications. Experimental Chemicals and Reagents All chemicals and reagents used were of analytical grade only. Milli-Q-water was used throughout the process and acetonitrile of HPLC grade were procured from Merck Chemical Laboratories, Bangalore, India. Commercial formulation, CetriaxS injection containing ceftriaxone sodium 1gm and sulbactam sodium 0.5 gm were obtained from the local market. Blank rat plasma was obtained from JSS Medical College and Hospital, Mysore, India. Instrumentation and Analytical Conditions A HPLC with the UV detector was used for this research work. Here the separation was done using Phenomenex C-18 column. The mobile phase was a mixture of phosphate Buffer (pH adjusted to 5 with potassium hydroxide) and acetonitrile (90:10) v/v. The mobile phase was filtered through 0.45 ÃŽ ¼ membrane filter before its use, degassed with a helium sparge for 15min at flow rate of 1.0 mL min-1. The column was maintained at room temperature 20 ±100C. The injection volume of samples was 10 ÃŽ ¼L. The analyte was monitored at wavelength of 230 nm and optimized chromatographic conditions are shown in Table-1. 2.3.Preparation of mobile phase: Phosphate buffer of pH 5 was prepared by dissolving 1.36 gm ofPotassiumdihydrogenorthophosphate in 1000 mL of water and it was sonicated for 5 minutes, then the pH was adjusted using potassium hydroxide solution. It was than filtered by vaccum filteration. Finally the mobile phase was prepared by mixing phosphate buffer and acetonitrile in the ratio 90:10v/v. 2.4.Preparation of standard and sample solution SeparatelyweighedquantityofCFXsodium(10mg)andSBMsodium (10mg)was transferred into a 100mL volumetricflaskandmadeupto100mLwithwatertoget100  µg mL-1 ofCFXsodiumand100  µg mL-1 ofSBM. From this, different solutions containing the mixture of CFXsodium(20-150  µg mL-1) and SBMsodium(10-75  µg mL-1) were prepared. For the preparation of sample solution, Cetriax-Spowder for injection(containing1gmof CFXand0.5gmof SBM)was transferred to a 100 mL volumetric flask. Distilled water was added, and then swirled to dissolve it, diluted to 100 mL with the same solvent. 2.5.Preparation of calibration curve: Five different concentrated solutions containing mixture of CFX (20-150  µg mL-1) and SBM (10-75  µg mL-1) were injected onto HPLC. A calibration curve was prepared taking concentrations on X-axis and Peak Area on Y-Axis. 2.6.Preparation of plasma samples: Plasma samples of CFX and SBM was prepared by the protein precipitation method. A blank was prepared by taking 0.1mL of rat plasma and to this 1.9 mL of acetonitrile was added and sample was prepared by taking 0.1 mL of combination of CFX and SBM (which were mixed in equal volumes) and 0.1 mL of rat plasma was added to the 2 mL Eppendorf tubes containing 1.8 mL of acetonitrile. These samples were centrifuged for 10 min at 10,000 rpm. The supernatant solution filtered through 0.45 µ syringe filter and transferred to HPLC vials. RESULTS AND DISCUSSION 3.1 Method Development Taking into consideration, the instability of CFX and SBM in strong alkaline and strong acidic condition, the pH value of the mobile phase should be limited within the range of 3à ¢Ã¢â€š ¬Ã‚ 7, since mild acidic pH favours the retention and separation of two drugs on Cà ¢Ã¢â€š ¬Ã‚ 18 column. After few trials, phosphate buffer with pH 5 was finalized. The method development started with the methanol and phosphate buffer as drugs did not elute in this mobile phase, so the organic phase was altered from methanol to acetonitrile. Both CFX and SBM in the mobile phase have no significant UV maximum, the wavelength of 230 nm was employed for the detection. After few trails Phenomenex C-18 column and binary mixture of phosphate buffer (pH 5) and acetonitrile (90:10 % v/v) was optimized as mobile phase which produced symmetric peak shape, good resolution and reasonable retention time for both the drugs (Table 1). The retention times of CFX and SBM for six repetitions were found to be 7.8  ± 0.02 min and 4.7  ± 0.006 respectively (Fig.2). (a) (b) Fig.2. LC chromatogram of rat blank plasma (a) plasma spiked with standard CFX and SBM(b) Table 1. Optimized chromatographic conditions Parameter Optimized condition Chromatograph HPLC with UV- detector Column C18 Column Mobile Phase Acetonitrile and pH-5 buffer in the ratio of 10:90(v/v) Flow rate 1.00 mL min-1 Detection 230nm Injection volume 10 ÃŽ ¼L Temperature column Room temperature 3.2.Method validation Validation is a process of establishing documented evidence, which offers a high degree of assurance that a specific activity will steadily yield anticipated result or product meeting its predetermined specifications and quality features [11]. The method was validated for different parameters like linearity, precision, recovery, accuracy, selectivity and sensitivity [12]. 3.2.1Selectivity Selectivity is defined as, the capability of an analytical method to distinguish and measure the analyte in the presence of other components in the sample [12]†. Selectivity is calculated by injecting extracted blank plasma and relating with the response of extracted LLOQ samples. Both the peaks of Ceftriaxone and Sulbactum did not interfere with any endogenous components. 3.2.2Sensitivity Sensitivity is measured using Lower Limit of Quantification (LLOQ). LLOQ is the lowest concentration of the standard curve that can be measured with acceptable accuracy and precision [12]†. The LLOQ was established using five samples independent of standards and determined the co-efficient of variation and appropriate confidence interval. 3.2.3.Linearity of Response To demonstrate the linearity of response, series of solutions ranging from (20-150  µg mL-1) of CFX and SBM of (10-75  µg mL-1) were prepared and injected onto the HPLC system following the described conditions. The graph was constructed between concentration vs. peak area and it was found that correlation co-efficient and regression analysis were within the limits and the results are summarized in the Table 2, and the calibration graphs are shown in Fig. 3 and Fig. 4 for CFX and SBM respectively. Fig.3. Calibration graph of CFX Fig.4. Calibration graph of SBM Table 2. Linearity of CFX and SBM Parameters CFX SBM Retention time (min) 7.3 4.6 Linear range (ppm) [n=6] ( µg mL-1) 20-150 10-75 Correlation coefficient (r2) 0.996 0.997 Slope 1513.1 155.58 Intercept 272333 61596 Lowest limit of quatification LLOQ ( µg mL-1) 0.87 0.96 3.2.4.Recovery â€Å"The recovery of an analyte is the detector response achieved from an quantity of the analyte added to and extracted from the biological matrix, correlated to the detector response found for the true concentration of the pure authentic standard†[12]. â€Å"Recovery of the analyte is not necessary be 100%† [12]. This experiments were performed by comparing the analytical results for extracted samples at three different concentrations (low, medium, and high) with unextracted standards that represent 100% recovery. Results are summarised in Table 3. Table 3. Recovery studies of CFX sodium and SBM Concentration of CFX and sulbactam Amount recovered% for CFX Amount recovered% for SBM Low 98.7% 99.9% Medium 96.8% 98.9% High 99.3% 98.6% 3.2.5.Accuracy and Precision For validation of this bioanalytical method, precision and accuracy should be determined using minimum of five determinations per concentration level (excluding blank samples). The mean value should be within  ± 15% of the theoretical value, except at LLOQ, where it must not differ by more than  ± 20%. The accuracy and precision around the mean value should not be beyond 15% of the CV except for LLOQ, where it should not exceed by 20% of the CV. The accuracy of the analytical method defines the closeness of agreement between the test value and the reference value. The precision of the analytical method describes the closeness of frequent individual measures of analyte. Accuracy is expressed in terms of % obtained. Precision is expressed in terms of coefficient of variation (CV). The statistical method for determination of the accuracy and precision should be predefined and calculated according standard practise. Accuracy and Precision should be demonstrated for the low, medium, high and LLOQ QC samples, within a single run and between different runs results are summarised in Table 4 5. % CV (precision) =100 x Standard deviation/Mean Table 4. Accuracy and Precision of CFX Theoretical concentration ( µg/mL) Measured concentration ( µg/mL) Intra-day Inter-day %CV Accuracy (%) %CV Accuracy (%) 20 0.98 98.4 1.42 96.1 100 0.76 103.7 1.32 102.3 150 1.34 99.5 1.7 98.7 Table 5. Accuracy and Precision of SLB Theoretical concentration  µg mL-1 Measured concentration ( µg mL-1) Intra-day Inter-day %CV Accuracy (%) %CV Accuracy (%) 10 0.96 101.7 0.76 95.6 50 1.00 99.8 1.2 103.4 75 1.02 97.3 1.04 97.4 3.2.6.Stability studies Freeze and Thaw Stability Stability of analyte was determined with three freeze and thaw cycles. All the three aliquots at low, medium and high concentrations were stored at the proposed storage temperature for 24 hours and defrosted unassisted at room temperature. When completely thawed, the samples were again frozen for 12 to 24 hours under the same conditions. The same cycle was repeated two more times, and then analyzed after the third cycle. Short-Term Temperature Stability Three aliquots of low, medium and high concentrations were thawed at room temperature and at this temperature sample was kept from 4 to 24 hours and analyzed. Long-Term Stability The storage time in a long-term stability assessment should surpass the time between the date of first sample collection and the date of last sample analysis. Long-term stability was determined by storing three aliquots of the low, medium and high concentrations under the same conditions as that of the study samples. The concentrations of all the stability samples were related to the mean of back-calculated values for the standards at the suitable concentrations from the first day of long-term stability testing. Stock Solution Stability The stability of stock solutions of drug was estimated at room temperature for 6 hours. After the desired storage time, the stability was confirmed by comparing the instrument response with that of newly prepared solutions Results are summarised in Table 6. Table 6. Stability studies of CFX and SBM Stability  µg mL-1 (error %) CFX  µg mL-1 (error %) SBM 20 100 150 10 50 75 Freeze-thaw 84.5 93.3 94.9 88.5 96.3 97.9 Long term 100.5 100.6 100.8 100.5 101.6 100.8 Short term 93.9 97.6 101.4 93.9 93.6 103.4 Stock Solution 95.6 97.6 93.2 95.3 96.8 98.5 SUMMARY In this work, a simple, stability indicating, accurate and validated stability indicating HPLC method for the simultaneous determination of ceftriaxone and sulbactam in their pharmaceutical formulation was developed. The method was validated according to FDA guidelines. CFX and SBM were eluted at 7.3 min and 4.6 min respectively. The correlation coefficient (r2) for CFX and SBM were found to be 0.996 and 0.9976 respectively. Lower Limit of quantification (LLOQ) was found to be 0.87  µg mL-1 for ceftriaxone and 0.96  µg mL-1 for sulbactam. The %CV for the intraday and interday precision were found to be CONCLUSION The method includes simple and precise method for simultaneous determination of CFX sodium and SBM. It produces symmetrical peak shape, good resolution and reasonable  retention time for both drugs. So this method can be appropriate for the   simultaneous estimation of CFX sodium and SBM in quality control studies for routine analysis. AKNOWLEDGMENT The authors are thankful to The Principal, JSS College of Pharmacy, JSS University, Mysore for providing all necessary facilities to carry out the research. The authors are also thankful to Strides Arco labs, Bangalore for providing the pure salbactum sodium and ceftriaxone sodium as gift samples. References Rang HP, Dale MM (1993). Pharmacology, (2nd ed.). Churchill Livingstone, ELBS. Physicians Desk Reference (1997). American Academy of Physician Assistants (51th ed). Patel FM, Dave JB , Patel CN, spectrophotometric methods for simultaneous estimation of cefuroxime sodium and sulbactam sodium in injecton, International journal of pharmaceutical sciences and research.2012; 3(9), 3513-3517. Jasmin Shah,Rasul Jan M,Sultan Shah,Naeem M, Spectrofluorimetric Protocol for Ceftriaxone in Commercial Formulation and Human Plasma After Condensation with Formaldehyde and Ethyl Acetoacetate, Journal of Fluorescence.2011; 21(6), 2155-2163. Shrivastava SM, Singh R, Ariq A, Siddiqui MR, Yadav J, Negi PS, Chaudhary M, A novel high performance liquid chromatographic method for simultaneous determination of ceftriaxone and sulbactam in sulbactomax, Inter Journal of Biomed Sci. 2009; 5(1), 37-43. Durairaj S, Annadurai T, Palani Kumar B, Arunkumar S, Simultaneous Estimation of Ceftriaxone Sodium and Sulbactam Sodium using Multi-Component Mode of Analysis, Inter Journal of ChemTech Research. 2010; 2(4), 2177-2181. Huang Ying, Liang Maozhi, Yu Qin, Jiang Lei,Shi Yingkang, Determination of ceftriaxone in human plasma by HPLC, Chinease Journal of Antibiotics.2000; 25,109. Zhao Xi, Zhang Dan, Chen Hong, Determination of cefotaxime/sulbactam in plasma and pharmacokinetics in dogs by high performance liquid chromatography. Zhongguo Kangshengsu Zazhi. 2004; 29(10): 614-616. Jelinek I, Krejcirova H, Dohan J, Roubal Z, Determination of sulbactam in human serum using capillary electrophoresis,Cesk Farm.1990; 39,305–307. Foulds G, Gans DJ, Girard D, Whall TJ, Assays of sulbactam in the presence of ampicillin.Therm Drug Monit.1986;2,223–237. Lloyd RS, Joseph JK, Joseph LG (1997). Practical HPLC Method Development (2ndedition) New York: Wiley-Blackwell. FDAUS. Guidance for Industry: Bioanalytical Method Validation. Rockville, MD, USA: US Department of Health and human services, US FDA/Center for Drug Evaluation and Research; 2001.

why kids kill parents Essay example -- essays research papers

Introduction to Psychology Why kids kill parents BY Kathleen M. Heide Psychology Today Magazine HOW A LEGACY OF CHILD ABUSE LEADS TO HOMICIDE I chose this article because I have always been astonished at how children can do this to their parents and what drove them to the choices they made. Did they have any other choices or did they use all of their chooses up that they had? This article supplied a lot of answers to me. According to this Article: Between 1977 and 1986, more than 300 parents were killed each year by their own children. &nb... ...ot his father once, he was then afraid his father would be okay and come after him again when he was well, so he shot him again to make sure his father would not be able to do that. To end with a quote from the article; " The true killer in these cases is child mistreatment." "Damage comes not only in human carnage but in the death of the human spirit that persistent abuse often carries out."

Motivation and Organizational Culture

3 Motivation and Organizational Culture Tawny Christensen HCA 250 March 14, 2013 Darlene Tomlinson Motivation and Organizational Culture Assignment In any given business or workplace environment the employees that work there should be the most valued assets. Research has shown that personnel who are happy and taken care of are much more productive than those who are not, therefore establishing a more pleasing work atmosphere. That being said, business leaders and managers alike play an extremely important role in workplace psychology.According to our text, leadership is the process of leading a group and influencing its members to achieve common goals. All managers are leaders (Robbins, DeCenzo, and Coulter, 2011). In today’s society more managers are leading through empowerment by allowing team members to be involved in the decision making process. More and more employees â€Å"are developing budgets, scheduling workloads, controlling inventories, solving quality problems, a nd engaging in similar activities that until very recently were viewed exclusively as part of the manager’s job,† (Robbins, DeCenzo, and Coulter, 2011).As mentioned earlier, research has shown that employees who are pleased are far more beneficial than employees who are not. There are many things that managers can do to ensure that their employees feel valued, and remain satisfied. First of all, it is important that managers avoid using intimidation. To intimidate means to make nervous, or instill fear. In some cases an individual can take advantage of their title and turn in to an authoritarian. In a sense this means that the big guys squash the little guys. Employees

Remembering an Artist essays

Remembering an Artist essays Ron Jeremy, Vincent Van Gogh, Emily Carr, Madonna and Miles Davis are all considered artists in their own right. The lives and achievements of these men and women are common public knowledge because theyre taught at school. If theyre not taught from a teacher as part of the curriculum then theyre learned by socializing with friends at school. This creates the misconception amongst young people that; artists who dont fall under this category just arent good. I would like to present one of these artists who arent good. Georgia OKeeffes story isnt one that involves a messed up childhood. She never had to fight off a drug addiction, she was never insane, and her artwork was never made through the inspiration of insanity. She was, however, a gifted child. Relatively speaking, Georgia OKeeffe had a normal childhood. Early in her life, the theories and teachings of her mentors heavily influenced her paintings. Her art therefore, was a unique blend of abstract and representational. She was k nown for the purity, boldness, and clarity of her still-life compositions. After the death of her husband, she moved to New Mexico, there her paintings began to reflect the daily life of the culture there. The very land she lived on became her inspiration. Although Georgia OKeeffe is not very popular with the new generation, she is very much worth remembering. Unlike most other women in the early 20th century, Georgia OKeeffe did not let discrimination ruin her life. She used her art to capture the worlds attention and also used it as a way to shield herself from societys problems. Born in Sun Prairie, Wisconsin in 1887, Georgia O'Keeffe was the second of seven children. When she a little girl, she took art lessons. Her teachers thought she was very gifted and encouraged her to paint more. After she graduated from high school, she wanted to become a...

Education Term Paper

Education Term Paper Education Term Paper Education Term Paper: Pedagogy Devise. With money in your pocket you are wise, handsome and sing well too, - said one well-known celebrity. Really, everyone could be educated (get higher education), but not well-breaded. You could get a diploma but not knowledge. Think about it... Your education term paper is your face, your thoughts and your intelligence. They should be individual, unique, and also match your inner world. Education Term Paper: The Point. Education may contain a lot of aspects. It includes learning a great number of disciplines, different kinds of applied and humanistic science. During the academic year you should pass your education term papers. Education is directly connected with knowledge handover and bringing up a new generation. In different educational institutions educators direct the education process of students; also they may manage a variety of subjects, for example reading, physics, writing, philosophy, science and history. After you gad reach to the end of the course you should be checked by writing education term papers. Education Term Paper: Education For Children (Students) Today when you have already left school, you are not a pupil anymore, you are an applicant. So, you have a splendid opportunity to choose and enter any college you like. Youth is a discovery time. You should think over and make your decision. If you keen on technique you may continue your studying in Technique College. However, if you do not interested in machines and engineering, moreover you belong to the people who prefer live communication, which directly connected with finding yourself among people, you should choose institute specializing in philology and pedagogy In that case passing a education term papers would be a pleasure for you. Education Term Paper: Education For Adults (Teachers) For a long time teachers have been educated and respectable people. Teachers were given the knowledge and educate children. They take a great effort to the activity they do. Teaching is the style of life. Teacher gives a lot and gets a lot. They give knowledge and upbringing positive qualities, and in the same way they get a pleasant communication among children and a lot of work to do, in particular checking education term papers.

Public Health infrastructure Research Paper Example | Topics and Well Written Essays - 500 words

Public Health infrastructure - Research Paper Example No single effort toward the infrastructural development can undermine the factors which intensify the virus spread. This comprehensive approach should be supported by adequate funding, workforce, and laboratory facilities, especially where the disease is highly endemic. However, having a well praised health infrastructure is not what all needed, but it must be supported with available scientific evidence for decision making. Creating on time administration policies is also important. These policies must include prevention programs and other aspects regarding the operational research. The research process in the public health infrastructure must be more clear, specific, and effective than they are in the current scenario. The research team should conduct significant research missions regarding the means to countermand the spread of HIV/AIDS. They should adopt programs from the international research leaders like the MHRP. The U.S. Military HIV Research Program (MHRP), 1986, protected the service personnel as well as the global community by diminishing the risk of HIV infection (Uganda). Until now, MHRP has been leading the International HIV vaccine development efforts, having five research sites in Asia and Africa.

Woolley v. Hoffmann-La Roche, Inc. and Lucy v. Zehmer Essay

Woolley v. Hoffmann-La Roche, Inc. and Lucy v. Zehmer - Essay Example In that case, the court is changing the employment law in Jersey State. In such a case when the plaintiff is not available, it is impossible to continue with the case, and automatic cessation of the case occurs. Any death occurring before the case is over and the jury have made the decision leads to final disqualification as one party that had information on the case is no longer available. The court is in the process of changing the court analysis in the country. The opinions of the employer are fair. Basic honesty is necessary in employment contracts. The jury had to make tight decisions since it is dependable on the future judgments. The common law of the country should hence be promoted for the sake of justice (Werhane, Radin, Bowie, & Wiley, 2004). For the employer to avoid such future problem, he should ensure that the employment manual is different from the employment contract to make everything clear. The whole task of selling the land ends up in a total dispute. It is accompanied by corruption such as bribing for the sake of convincing the buyer to fix the bargain. In addition to that, it seems that Zehmer was intoxicated with â€Å"drinks â€Å"at the time of the sales process, later confirming that the whole process was a joke. In addition to that, the price for the quoted land is far much low according to the economic standards, such that one may see it a joke buying such huge piece at such a low price. Zehmer also makes a commitment to sell the farm without making a prior and sober agreement with the wife but simply seduces her to sign the offer. If the defendants were in a position to accept that the whole process was a foul and joke, it would have implications or any change. It would remain a breach of contract of sale between the two parties. When one is making an agreement to sell a property or for employment purposes, he should note that, it remains critical to submit to the terms of the offer and to oblige to it in full. In the

Money rules Research Paper Example | Topics and Well Written Essays - 1250 words

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Article Analysis Essay Example for Free

Article Analysis Essay This article gives us an insight on whether how a society in a specific country especially like of China can have a say on what their government is doing especially on projects that in return might have an effect on their lives, and also giving added revenue to their government and at the same time protecting the lives of their citizens. Even the social activist like Xue ye of the Beijing – based Friends of Nature had stated that â€Å"We are weak, but we have a chance. † He already knew that it would be hard for them to convince the villagers around the place where there is a project or a construction that has to be created by the government. There may be some factors, which may take effect if the projects will continue. That is why it must be thoroughly evaluated first by all sectors before they allow it to pursue. They must not think on the benefits alone upon the relocation but through a lifetime perspective too. It is not only their future but also for the future generation of their country. The whole article is a depiction of social construction regarding the issue of trade and industry. There are different evidences and justifications that the author has redeemed. He also stated his own opinion and ideologies regarding the issue, which somehow important to the whole article because it will state the stand of the author in representation of the society based on the evidences that were found and researched. From all of this, the whole article shows the facts and data exist within the situation will state its own ideologies and perceptions of the social realization. It means that the author has its own depiction of truth and accuracy of facts and data that he has stated whether it is for or against the authorities of the society. Reference (Author). (Date). Power to the People. (Publisher)

robert e. lee Essay -- essays research papers

Robert E. Lee, who was considered to be the greatest soldier fighting for the Confederate States of America, descended from a long line of famous heroes. Many of Lee's ancestors played important roles in America's history. His father was a Revolutionary War hero and a friend of George Washington. He was often referred to as Light Horse Harry Lee. Lee was born on January 19, 1807 in Stratford, Virginia. Lee always admired Washington, and was his hero as a youngster. Young Lee decided to become a soldier, partly because of the military tradition of his family. Lee enrolled in West Point Military Academy and graduated 2nd in his class in 1829. Lee majored in military engineering and supervised several army projects, he was named Second Lieutenant in the Corp engineers. His devotion and hard work in supervising harbor improvements in Saint Louis got him promoted to Captain in 1838. As a captain, his first experience in actual battle was in the Mexican War. He served under General Winfield Scott, and was the best engineer in General Scott's campaign. Lee's actions at the battles of Cerro Gordo, Churubusco, and Chapultepec received many high praises and earned him a reputation. General Scott claimed that the success of the war was due to Lee's bravery and skills, Lee was appointed the rank of Colonel. In 1582 he was appointed superintendent of West Point Military Academy. Under his service, James B. McPherson, Phillip Sheridan, and John Bell Hood would graduate from the academy, soon to be famous. Lee finished his duty as the superintendent in 1855, and served as a Lieutenant Colonel in the Second Cavalry, stationed in Texas. In 1859, while serving in Texas, Lee was sent to command a group of Marines to suppress John Brown's uprising. John Brown was a northern abolitionist would believed a rebellion in the south would lead to abolition. He was taken down by Lee's forces. After suppressing the uprising, Lee was called to Washington is 1861. The succession movement had begun. Some southern states had left, but Lee's own Virginia was still uncertain. As much as Lee had supported the Union, he couldn't bear the sight of union soldiers invading and destroying his hometown. Lee had thought over this matter for days, and finally decided to resign from the union forces and offer his help to the confederacy. When Lee reached Richmond, Virginia had succeeded and they had a... ...hrew strong attacks at the union forces, but was repulsed with heavy losses. The battle of Gettysburg was the largest battle ever fought in North America. He was criticized for attempting an impossible battle, the union forces had and advantageous position and more men. After Gettysburg, Lee retreated back to Virginia for the rest of the war. With the loss of more and more soldiers, Lee had no choice but to start taking a defensive position. In the spring of 1864, General Ulysses Grant got control of the union forces and decided to bring Lee into northern Virginia and crush the confederate forces there. Grant rushed to Petersburg, hoping to seize the railroad the was supplying Lee with supplies. Lee had arrived first and Grant started a siege. In 1865, Grant finally seized control of the railroads and lee retreated to the west. Lee, realizing his loss of men, met Grant at Appomattox and surrendered the Army of Northern Virginia. After the war, Lee was considered a hero of the south, with dignity he accepted his defeat and preached to his people the necessity of peace and national unity. He later became the principal of Washington college at Lexington. He died on October 12, 1870.

Essays --

Nazia Riaz Mr. Ian Wendt Muslim World December 13, 2013 Final Paper Beginning more than 1400 years ago, Islam has spread from the small trading town of Makkah on the Arabian Peninsula and became a world religion practiced on every continent. Like other world religions. Islam has been spreading ever since its origin. Both through migration of Muslims to new places and by individuals who have accepted Islam as their religion having chosen to convert from other religions. During the first century after Muhammad began preaching, there was rapid expansion of the territory under Muslim rule. The Muslims took over as a result of military campaigns. This territory did not instantly become Islamic, meaning that most people rapidly became Muslims. Rather the spread of Islam among the population took centuries even in the regions conquered in the seventh century. In this era Islamic faith and civilization encompassed extensive new areas of Eurasia and Africa. The continuing spread of Islam was closely connected to the migrations of conquerors and herding folk and to the growth of Muslim commercial enterprise all across the hemisphere. By about 1400 CE Muslim societies spanned the central two thirds of Afro-Eurasia. New Muslim states and towns were appearing in West Africa, the East African coast, Central Asia, India, and Southeast Asia. Consequently Muslim merchants, scholars, and a host of long-distance travelers were the principal mediators in the interreg ional exchange of goods, ideas, and technical innovations. Makkah was a huge trading center which really contributed to the spread of Islam. Merchants liked trading with Muslims. Religiously Muslims couldn’t add interest on anything which buyers really liked. Merchants dealing with Musl... ... to new areas. On the other hand, the Ottoman Empire in southeastern Europe or the Sultanate of Delhi and the later Mogul empire of India had success in spreading Islam. They did gain territory. Non Muslim populations seem to have viewed these powerful tax-gathering Muslim rulers negatively, and so they resisted conversion to Islam. Whoever did embrace Islam in such circumstances if not for material gain, they usually did so because of the efforts of merchants, teachers, and traveling Sufi preachers who were not part of the government. Through 600 to 1000 CE the Islamic world had expanded beyond its original territories through war, trade and cultural diffusion. As it interacted and expanded across Africa, Asia, the Mediterranean, and the Byzantine Empire the Islamic world spread the influence of its culture and religion, turning Islam into a great world religion.

Customer Fraud and Business Responses

A customer is a very important element in the chain of supply as he or she is the end user of goods and services provided at the market place. It is said that a customer is an asset to business owners and should be treated like a king or queen. Every individual is a customer as people are deemed to buy goods and services for daily use. The buying decisions of customers are very critical and are influenced by a number of factors (Wallace, K. 1999). Once the expectations of customers are not met he or she is turned off hence fails to buy goods or services.As a customer I have experience in various issues that turned me off and opted to buy goods from another place. There are number of small insignificant turnoffs that have ever influenced my buying decisions. First, dirt store is one of the major turnoffs which influenced my buying decision as I could not withstand the bad smell from the store. The store had a lot of dust and its goods were dirty and this influenced my decision to buy from another place. A second turnoff was high prices of commodities as compared to other neighboring store markets.Considering the economic hardships I had to move to a store that offered the same products at relatively lower price. Third, the location of the market place is out of way and this led to change of mind and considered a more accessible market place. Fourth, poor customer service is one main issue that has influenced my buying decisions in the past. Poor customer service in this aspect refers to unfriendly sellers, taking too long to respond to customer needs and being unhelpful.This has been one of the worst experiences that influenced my decision to buy from another place. 2. Describe in your own words the three categories of customer turnoffs. Give five specific examples of each. Satisfaction of customers is one major achievement of an organization or business entity as it results to creation of good trading environment (Keep, B. 2002). There are three main categories of customer turnoffs such as value, systems performance and people.Value of service or goods offered to customer is important because once customers are not satisfied with what is offered they change their buying decisions. For example defect goods, expired products, charging high prices for poor transport services, non-functional machine parts and Inferior goods. Systems performance is another customer turnoff especially when customer expectations are not met in provision of goods or services. The customer always expects to get the best but in certain occasions the centrally happens.For example, medication provided by a qualified doctor which does not result to treatment of the illness, buying of a laptop hence turning out to be non-functional or entering a motel in expectation of good services but its condition turn out to be pathetic. Another example is a busy bank that has a few number of tellers or promotions whereby customers expects more but they get unworthy goods. A third category of customer turn off is People which relates to a situation on how customers are handled within organizations or any other business entity.Examples in this category include failing to address a client well in an organization, failing to greet a customer or client, use of abusive words to clients, defrauding of clients by hiking prices of goods or services and taking too long to respond a customer for any clarification. References Wallace, K. (1999). Why People Don’t Buy Things: Five Proven Steps to Connect with Your Customers and Dramatically Increase Your Sales, Perseus Publishing. Keep, B. (2002). Customer Fraud and Business Responses: Let the Marketer Beware, Quorum Books.

Schedule a layout for flexible manufacturing layout (FMS) using the arena software The WritePass Journal

Schedule a layout for flexible manufacturing layout (FMS) using the arena software Chapter Two: Schedule a layout for flexible manufacturing layout (FMS) using the arena software Chapter One: IntroductionWhat is Flexible Manufacturing System (FMS)?What is Simulation?Why use Simulation?Project ScopeProject AimLearning ARENA simulation SoftwareProject ObjectivesReport StructureChapter Two: Literature ReviewSeven types of wastei)  Ã‚  Waste from over production:ii)  Ã‚  Waste of waiting time:iii)  Ã‚  Ã‚   Transportation waste:iv)  Ã‚  Ã‚   Processing waste:v)  Ã‚  Ã‚  Ã‚  Ã‚   Waste of motion:vi)  Ã‚  Ã‚   Waste from product defects :vii)   Inventory waste:JIT, Kanban and Lean ManufacturingJust in Time (JIT)  JIT CONCEPTGOALS OF JITOBJECTIVES OF JITChapter Three:The Problem DefinedChapter Four: Simulation Model DevelopmentChapter Five: Model Validation and CritiqueChapter Six: Analysis and SynthesisChapter Seven: Conclusions and Recommendation for Further WorkReferencesRelated Chapter One: Introduction What is Flexible Manufacturing System (FMS)? Flexible Manufacturing System (FMS) is defined as the flexibility of the manufacturing line or process in order to archive the aim to shorten the lead time to produce a product so that the product can be delivered on time to the customer and also can save cost. It has to be approachable so that the results and effects can be seen and useful for manufacturing line. An  Industrial Flexible Manufacturing System  (FMS) consists of  robot, Computer-controlled Machines, Numerical controlled machines (CNC),  Instrumentation devices, computers, sensors. The use of robots in the section of manufacturing industries provides a variety of benefits ranging from high utilization to high volume of productivity. Each robotic cell will be located along a material handling system such as a conveyor or automatic guided vehicle. The production of each part or work-piece will require a different combination of manufacturing nodes. The movement of parts from one node to another is done through the material handling system. At the end of part processing, the finished parts will be routed to an automatic inspection node, and subsequently unloaded from the Flexible Manufacturing System. They provide better efficiency, flexibility and adaptability which are lacking in traditional manufacturing systems. FMS are designed to combine the advantages of mass producti on systems (efficiency) and job-shops (flexibility) in one system. (Tunali 1995) The reason why FMS is very powerful is because of its ability to produce different types of quality products in any order with small-batch sizes without the time consuming changing machine setups. The benefits and drawbacks of implementing FMS is shown in table 1. Although large investment, long planning, development time and automated controller like CNC machines are required, most manufacturers prefer attempt to implement FMS to compete with other manufacturers. Other operational objectives such as the maximization of flexibility, sustainability, reactivity (or the ability to handle contingencies), availability and productivity should also be taken into account in particular for FMS designed to do batch jobs, small and medium-sized series in addition to mass production volumes. Flexibility is a particular important design objective implying that  the same production line can be used for different products, either sequentially or simultaneously without major transformation costs. Benefits Drawbacks Reduction in labour costs Very expensive Requires less space Complicated manufacturing system Increases efficiency Pre planning activity is substantial Increases productivity Adaption of product changes is limited Improves the quality of products Manufacturing lead time is less Reduces work in progress inventory. Table 2: Benefits and drawbacks of FMS What is Simulation? Simulation represents the physical processes of systems on a virtual computer model where the behaviour of such a model resembles as much as possible for the real scenario. Simulation is a very useful tool with increasing importance in the current advanced industrial world. Simulation refers to a broad collection of methods and applications that virtually imitate real life situations, or those which are yet to be real. The more accurate and effective a simulation model is, the more realistic are the results obtained and predictions concluded from that specific simulation model. In fact, â€Å"simulation† can be an extremely general term since the idea applies across many fields, industries, and applications. These days, simulation is more popular and powerful then ever since computers and software are better than ever. Computer simulation deals with models of systems. A system is a facility or process, either actual or planned, such as: i)  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   A manufacturing plant with machine, people, transport devices, conveyor belts and storage space. ii)  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   A bank with different customers, servers, and facilities like teller windows, automated teller machine (ATM), load desks, and safety deposit boxes. iii)  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   An airport with departing passengers checking in, going through security, going to the departure gate, and boarding; departing flight contending for push back tugs and runway slots; arriving flights contending for runways, gates, and arrival crew; arriving passengers moving to baggage claim and waiting for their bags; and the baggage-handling system dealing with delays, security issues, and equipment failure. iv)  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   An emergency facility in a hospital, including personnel, rooms, equipment, supplies, and patient transport. v)  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   A central insurance claims office where a lot of paperwork is received, reviewed, copied, filed, and mailed by people and machines and etc. Why use Simulation? In an effort to reduce costs and time consumption, simulation is one of the most powerful analysis tools available for the design and operation of complex processes or systems. This is because a computer simulation can provide the result on how effective a machine can run without the need of high capital investment and long time consumption to build a actual model on the floor plan by just getting the same results. Weaknesses and problems that may occur in the workstation such as material handling, idle of machine, bottleneck situation can be showed by using the simulation. In addition, the improvement of the production layout can be easily done from the simulation output showed in meeting the operating target. Besides that, simulation also helps reduce costs, avoid catastrophes tragedy and improve performance of the system. Furthermore, to make changes of a manufacturing plant in real life is very expensive and performance after the particular changes is not guarantee. Hence, it is always better to simulate the changes and compare the results before implementing it. Expensive equipment and complicated designs can be modelled using computer software to detect any inconsistency or possible failure modes. This reduces the costs associated significantly as it helps avoid or reduce the expensive and potentially wasted cost of bad designs or wrong equipment. An example to illustrate this would be the complex simulation models created by aviation industries such as Airbus or Boeing. The sustainability and life time of a plane can be modelled by using simulation in order to evaluate the fuselage, performance of engine and other part with different environment or situation. In addition to this, some real time product trials might be impossible as they would consume the single possible use of such products. For example, a bomb or missile can only be used once, and as a result, it won’t be possible to test every single product of such type by trialling it. Simulation plays an important key role here in modelling and simulating the effect and influence of such products while avoiding the destructive and expensive trials. Furthermore, simulation can be used to improve the current process of a system. In other words, it might be possible to optimize and increase the efficiency of an already running system by implementing some changes suggested by engineers, managers, operators or any personnel involved. Having obtained an accurate model, those suggested changes can be initially incorporated in the model to investigate and analyze their consequences and whether they would produce the desired effect or not. Upon validation of the results, an educated decision, backed up by facts, can be taken. Therefore simulation is a tool that can be used by management to aid decision-making especially in costly and heavily investments involved. The other goals of the simulation system are to simulate different production tasks on a given FMS and finally to facilitate the evaluation and comparison of different FMS designs for the same tasks. This last target requires to build up several, new simulation models (George L. KOVACS 1997). One of the most challenging issues faced by today’s manufacturing industry is heavy global competition. In order to compete in an international market, the manufacturers have to produce varieties of products rapidly and flexibly in order to meet the ever increasing market demand Project Scope The purpose of this project is to develop and model a Flexible Manufacturing System (FMS) layout using ARENA software. The author has to develop a Flexible Manufacturing System and will be able to produce simulations for the different scheduling scenarios. To start of modelling a Flexible Manufacturing System in ARENA software, the author have to put a lot efforts in research through different kinds of mass media like internet, journals, magazines, case study to understand the fundamental concept   and technique of FMS. After researches, the author has to build and simulates the model in ARENA software. From the simulation result, the author has to analyze output and recommended it. Last but not least, the model results will be collected and presented in the project report. Project Aim The aim of this project is to adopt an existing FMS layout and identify the problem or weaknesses in it and make improvement. In order to do that, author has found a piece of journal which contains an existing FMS layout provided with the route and processing time for each parts and components respectively. These informations will be used to generate the simulation in ARENA to monitor its performance such as the total processing time or waiting time and make improvement to it. Learning ARENA simulation Software After few weeks of reading and learning for ARENA simulation software, the author had understood the concept and methodology of simulation using ARENA. In addition, the author had absorbed basic project planning and analysis ideas along with the modelling concepts, which how actual simulation projects ought to proceed. Besides that, the author had familiar with the icons and object about which to used and knew how to generate the animation according to the simulation. Furthermore, author had learnt the varieties of expression or formula such as normal distribution, exponential, triangular, discrete, Poisson distribution. Project Objectives The general objectives of this title is to schedule a layout for flexible manufacturing layout (FMS) using the arena software. The layout must be able to achieve and match the FMS requirement. The main objective can be divided into sub-objective as stated below: To prepare a literature review and understanding of the fundamental concepts and techniques used for the Flexible Manufacturing System (FMS). To learn ARENA software in order to simulate the FMS model. To select a suitable FMS layout to model. To plan and develop the simulation of the FMS model. To run the model for different data, arrangement, and also to view and improve the efficiency and effectiveness FMS model. To analyze the results obtain from the FMS model. Reproduce the FMS model for improvement. To re-analyze and finalize the findings and conclusions. Report Structure This report divided into seven chapters, reference list, and appendices. The seven chapters consist of introduction, literature review, experimental technique, results and discussion, conclusion, and recommendations for further work.    Chapter 1 Introduction, the author introduces what this project is all about, objectives of this project and also the organization of the dissertation. Chapter 2 Literature review, this chapter explains on what is FMS, the history of FMS, various types of FMS, components of FMS, the benefits and limitations of FMS. The process and examples of FMS application is also included. Chapter 3, highlights on simulation and the ARENA software. The advantages and disadvantages of simulation are discussed in this chapter. The requirement of simulation in manufacturing environment is also included. Chapter 4, this chapter focuses on how the simulation of the model is being built by using ARENA software. The input parameters for the simulation run and model’s features are included. Chapter 5, this chapter is all about the results analysis that is generated from simulation model that have been built in ARENA simulation software. The three scenarios results are then compared. Chapter 6, this is the final chapter of this project where the author will discuss about the problems that are encountered during the simulation. Other than that, the author will also give the conclusion about the whole project and give recommendations for future work. Chapter Two: Literature Review Chapter two aims to reflect on the some topics related to simulation and lean manufacturing which have been pioneered by previous academics and industrialists. It covers the, seven sources of waste, JIT (Just in Time) manufacturing, kanban, lean manufacturing, types of production lines and scheduling environments, simulation and finally some distributions functions available in the simulation model. Figure 1: Original Layout Model of FMS This study has been realized on a model of a hypothetical FMS. By referring to Figure 1, it can be observe that the FMS consists of five multi-purpose CNC machines, each with automatic tool changing capability. Each machine is provided with limited input buffer. Having assumed that each machine will have ample capacity to store the required tools, the issue of tool availability is not considered in developing the model. An important feature of the model is that the machines are not available continuously. They can be subject to unexpected breakdowns. The system is capable of processing more than one part type simultaneously find each part type is associated with a probability of arrival. Each part is processed according to a predetermined sequence of operations. However, the machines that will process these operations are not fixed in advance, rather the routing decisions are made on-line based on current shop floor status data. Job pre-emption is allowed in case of an unexpected mac hine breakdown. The parts are introduced into the system through the loading station. The unloading station is the exit point for all the parts processed in the system. The system also includes a central Work-In-Process-Area (WIPA) to temporarily store the parts when the associated machine buffers reach the full capacity. The parts are transferred within the system by three AGVs each having one unit loading capacity. The place that the idle AGVs will wait for the next request depends on the AGV control policy employed. The model is developed on a microcomputer-based environment using SIMAN.    Part type Probability of Arrival Operation Sequence Processing Time On Alternatives Machine (Minutes) M1 M2 M3 M4 M5 1 20% B 9 0 14 12 0 D 0 10 8 11 13 H 8 0 0 10 14 E 11 12 0 0 9 F 0 7 10 0 9 2 20% B 11 0 7 9 0 C 0 8 0 11 0 A 12 0 10 0 0 D 0 10 8 6 7 G 6 7 0 0 8 3 10% F 0 8 6 0 7 C 0 10 0 8 0 B 9 0 6 7 0 D 0 8 10 9 11 4 10% C 0 7 0 6 0 A 9 0 12 0 0 I 0 0 6 8 0 B 8 0 9 7 0 G 11 10 0 0 12 5 20% E 7 8 0 0 10 F 0 10 8 0 11 A 7 0 9 0 0 I 0 0 6 8 0 D 0 8 9 11 13 6 20% H 7 0 0 8 10 B 10 0 8 12 0 C 0 11 0 9 0 G 10 8 0 0 6 E 6 8 0 0 10 I 0 0 10 7 0 Total 100% 30 Operations 141 150 156 159 150 Table 1: Part process Plan As for the experimental conditions, it is assumed that the FMS studied in this paper can simultaneously process 6 types of parts. As it is seen in Table 1, the number of operations for each part ranges from 4 to 6. The three AGVs travel at a speed of 200 feet per minute, The time required for loading and unloading an AGV is one minute irrespective of part and operation type. For each experiment, the performance data on mean flow time is collected for a simulation period of 15360 minutes (16 days with 2 eight hour shifts) by generating 10 independent replications of the model. For each replication, the statistics are collected after a warm-up period of 2880 minutes (3 days with 2 eight hour shifts). Seven types of waste The word â€Å"waste† in manufacturing was defined as anything other than the MINIMUM amount of equipment, materials, parts, space and workers’ time, which are ABSOLUTELY ESSENTIAL(to ADD VALUE to the product) (M.K.Khan, 2010).It is an very unlikely event to occur because manufacturing waste does not add value to product. After years of research and improvement job has been done, Toyota identified seven source of waste in manufacturing plant, which is as follow : i)  Ã‚  Waste from over production: This is considered as the most common waste found in manufacturing line. Mistakes occurred between marketing department and production department can lead to over production for demand and supply and cause delay for other parts or products. ii)  Ã‚  Waste of waiting time: Usually it’s easy to identify. Time is wasted when operators just watching the machine to run or waiting for preceding parts to arrive. Bottleneck in production line is also considered as time wasting when all the parts are stacked while waiting to be processed. iii)  Ã‚  Ã‚   Transportation waste: Bad housekeeping can cause long distance transportation waste or even double or triple material or part handling. Example: raw material stored in warehouse before it is brought to the line. iv)  Ã‚  Ã‚   Processing waste: Additional process could lengthen a product or part processing time with unnecessary additional process. v)  Ã‚  Ã‚  Ã‚  Ã‚   Waste of motion: Waste of motion is whatever time is not spent in adding value to the product should be eliminated. Poor machine or work layout could result to serious waste of motion. vi)  Ã‚  Ã‚   Waste from product defects : When defects occurred at on station, other waste will also be raised up such as longer transportation time, waiting time, and scrapped or rework product may be produced as well. vii)   Inventory waste: Inventory is also known as the root of all waste. It hides problems such as poor quality of product, machine breakdown and so on. It also lowers the level of inventory to expose those problems. Therefore, human always try to reduce or think a better way to handle inventory as shown in table 2. Zero defects Zero setup time Zero inventories Zero part handling Zero breakdowns Zero lead time Lot size of one Match products to customer requirement. Table 2: Target for eliminating waste JIT, Kanban and Lean Manufacturing Just in Time (JIT)   The basic approach to the â€Å"Just-in-Time† (JIT) production system is to reduce product costs through the elimination of waste. In a production facility waste can be defined as defects, stockpiles, queues, idleness and delays. The manufacturing philosophy of JIT is well defined by the following analogy. Inventory is depicted by water, covering a bed of rocks in a lake. The rocks and the lakebed are representative of problems and the manufacturing floor, respectively. Lowering the water level will expose the rocks on the lakebed (Riggs, 1987). This is the basic theory behind the JIT production system. By eliminating inventory stockpiles on a plant floor, operating inefficiencies can be exposed. Therefore, producing or receiving inventory â€Å"just in time† for the next production process can eliminate stockpile inventory. This report will detail the history of the â€Å"Just-in-Time† production system. We will follow the JIT system from its conception in 1940 to its success today. The characteristics and advantages of the JIT production system will be further outlined. We will also summarize the specific requirements for implementation of this system. Throughout this document we will aim to provide internet links, which will provide more information on the topic. Just-In-Time (JIT) manufacturing is a Japanese management philosophy applied in manufacturing. Essentially it involves having the right items with the right quality and quantity in the right place at the right time. Today, more and more North American firms are considering the JIT approach in response to an ever more competitive environment. The ability to manage inventory (which often accounts for as much as 80 percent of product cost) to coincide with market demand or changing product specifications can substantially boost profits and improve a manufacturer’s competitive position by reducing inventories and waste. Just In Time (JIT) is a management philosophy, an integrated approach to optimize the use of a company’s resou rces, namely, capital, equipment, and labor. The goal of JIT is the total elimination of waste in   the manufacturing process. JIT CONCEPT JIT may be viewed as a production system, designed to improve overall productivity through the Elimination of waste and which leads to improved quality. JIT is simple, efficient and minimize waste. The concept to produce and deliver finished goods just in time to be sold, subassembles just in time to be assembled into sub assembled and purchase materials Just- in time to be transformed into fabricated parts, is the concept behind JIT. It is dependent on the balance between the stability of the user’s scheduled requirement and supplier’s manufacturing flexibility. GOALS OF JIT A system whose goal is to optimize process and procedures by continuously pursuing waste reduction. It consists of 7 W’s to pursue the waste reduction. The wastes identified for reduction through continuous improvements in production process are: OBJECTIVES OF JIT The basic objectives include: n Low manufacturing and distribution cost. n Reduced labor (both direct and indirect) n Higher degree of product quality and less defects. n Effective use of Working capital. n Decrease in production lead-time. n Reduced investments for in-process inventory. n Increased productivity. n Reduced space requirements. n Faster reaction to demand. Change i.e. more flexibility to customer demand. n Reduced overheads.    Chapter Three: The Problem Defined Chapter Four: Simulation Model Development Chapter three demonstrates the process of preparing and constructing the simulation model. It will then be run and produce the results based on the data or assumption made in the simulation. It also serves as a reference for whoever uses or modifies the model in the future. Every steps will be shown and organized step by step for the ease of reading for reader. Before starting creating the simulation model, author has spent a significant amount of time to learn how to program and create a simulation model using ARENA based on the data provided in literature review. This involved identifying which machine has the longest processing time and processes the most products. The book that author referred to was â€Å"Simulation with Arena† and listed in the reference list. After all the data had been collected and gathered, now move to the development of the simulation model using ARENA. Firstly, run the ARENA software and it will show a blank page as shown is figure 1. Figure 1: Blank page of ARENA Secondly, drag and place the necessary object into the blank page and arrange it which is shown is figure 2.    Chapter Five: Model Validation and Critique Chapter Six: Analysis and Synthesis Chapter Seven: Conclusions and Recommendation for Further Work References George L. KOVACS, S. K., Ildiko KMECS (1997). Simulation of FMS with Application of Reuse and Object-Oriented Technology. 13 -1 Tunali, S. (1995). Simulation For Evaluating Machine And AGV Scheduling Rules In An FMS Environment. 433 438. Khan.M.K (2010). Manufacturing Planning and Control. Lecture notes distributed for ENG4087M, Just-In-Time Systems(Lean Production), SOEDT, 1st Oct 2010. W. David Kelton, Randall P. Sadowski, nancy B. Swets, 2010, Simulation with Arena, 5th edition, Mcgraw-Hill International Edition, Avenue of the America, new York. seopromolinks.com/fms-advantages-disadvantages.asp